Organization and Membership
OSC19 is dedicated to advancing drug discovery research for COVID19 for humanitarian aims. All results and data will be shared openly as much as possible. OSC19 will make no intellectual property claims and will not pursue patents. OSC19 members and the public may use OSC19 data and results for academic or commercial purposes provided OSC19 is credited.
We are currently focused on small molecule drug discovery for SARS-CoV-2 targets. We have particular expertise with computational and structure-based drug design although we are not limited to these techniques. We are currently working on the targets Mpro protease, nsp16 RNA methyltransferase, Spike protein, nsp15 endoribonuclease, and RNA polymerase. We are currently focused on repurposing known drugs and chemical reagents and investigating their close chemical analogs. Our research capabilities include computational screening, AI drug discovery, molecular dynamics simulations, chemical synthesis, biochemical and biophysical assays, X-ray crystallography, and in vitro BSL3 viral assays.
Senior Members (Lab heads)
Ho Leung Ng, Founder
Associate Professor of Biochemistry & Biophysics, Kansas State University, USA
Computational and experimental structure-based drug design. AI-driven drug design.
Michael Scott Long
Professional science writer
OSC19 writer and social media director. PhD in analytical chemistry.
Associate Professor and Dean, Al-Quds University Faculty of Pharmacy, Palestine
Abraham Karlapudi Peele
Assistant Professor of Biotechnology, Vignan’s Foundation University, India
Computational drug design.
Principal Investigator, CSIR-Open Source Drug Discovery, India
Data Scientist, National Center in Big Data and Cloud Computing, Pakistan
Senior Staff Scientist, Wistar Institute, USA
Biochemistry, assays, and crystallography for Mpro protease.
Assistant Professor, University of Southern California Keck School of Medicine, USA
Biochemistry and drug discovery.
Owner, AquaMem Scientific Consultants, USA
Associate Professor, Loyola University Stritch School of Medicine, USA
Biochemistry, computational drug design, assays, medicinal chemistry, epidemiology.
Chief Technical Officer, Zetane Systems
AI drug discovery.
SSGCID (Seattle Structural Genomics Center for Infectious Diseases), USA
Assays, protein expression, crystallography. Targets: nsp14, nsp15, nsp16.
Professor of Chemistry and Computer Science, University of Toronto, Canada
AI drug discovery, assays, computational chemistry, synthetic chemistry. Target: nsp16.
Professor, Kansas State University College of Veterinary Medicine, Director of the Center of Excellence for Emerging and Zoonotic Animal Diseases, USA
BSL3 SARS-CoV-2 viral assays.
Sponsor. DevCloud cloud computing. Intel software tools.
Cloud computing resources for scientific computing.
Dongbang FTL, South Korea
Gapibio, South Korea
Open Source Pharma Foundation, India/USA
Pioneer in open source drug discovery and development. Advisory.
Computational drug screening software.